2nd Century

20s
- 120
  - Death of Plutarch (approximate date)
  - Death of Tacitus (approximate date)
- 128
  - Aquila of Pontus, the second translator of Sacred Scripture from Hebrew after the Seventy, translated the Hebrew Scripture into Greek in the 12th year of Emperor Hadrian
- 129
  - Birth of Galen (approximate date)
30s
- 135
  - Death of Epictetus (approximate date)
- 138
  - Death of Emperor Hadrian
40s
- 145
  - Birth of Emperor Severus
50s
- 150
  - Birth of Clement of Alexandria (approximate date)
- 155
  - Birth of Tertullian (approximate date)
60s
- 160
  - Death of Marcion (approximate date)
- 161
  - Birth of Emperor Commodus
- 165
  - Death of St. Justin Martyr (approximate date)
70s
- 170
  - Birth of Philostratus (approximate date)
- 175
  - Birth of Aelian (approximate date)
- 178
  - Death of St. Symphorian (approximate date)
80s
- ~180
  - Theodotion, a proselyte Jew and former Marcionite, produced a Greek translation of the Hebrew Scripture under Emperor Commodus; his version in Daniel was received and followed by the Church
- 185
  - Birth of Origen (approximate date)
90s
- 192
  - Death of Emperor Commodus
- 198
  - Council of Palestine under Pope Victor defined that the world was created at the vernal equinox, that the first day of the world was March 25, and that Christ was incarnated on March 25
- 199
  - Death of Pope Victor I